Flow cytometry is a very powerful technique for rapidly analyzing large numbers of cells individually using light-scattering, fluorescence, and absorbance measurements. The use of multiple markers in polychromatic flow cytometry has a host of applications in both basic research, drug discovery, and the clinical laboratory. Cambridge Biomedical is setup to assist our clients with FACS assay development, validation, optimization and sample analysis needs.

• The capability to simultaneously analyze multiple parameters for a given cell population
• High throughput cell and particle based screening and analyses can be performed
• In depth analysis of complex cellular processes such as oncogenesis, cell cycle regulation, autophagy, apoptosis, necrosis, senescence, cell proliferation, and functional studies within phenotypically defined populations, such as calcium flux, and phosphorylated proteins.
• Can be used for intracellular and cytoplasmic antigen analysis, and organelle analysis
• Multiple applications include, but not limited to: DNA and RNA analysis, translocation assays, screening for ploidy, immunophenotyping, oncological and disease-associated biomarker analysis and monitoring, whole cell and receptor binding assays, cell counting, functional G-protein-coupled receptor screening, in vitro toxicology, antibody screening, and rare event analysis, such as in dendritic cells, and stem cells/progenitor cells

Equipment: Our facility offers FACSCanto II

Cambridge Biomedical is CLIA certified, CAP accredited, and provides services that support best laboratory practices and GLP compliance. We help our clients navigate through quality and regulatory requirements from preclinical to IV studies.